A medical front desk rarely does one thing at a time. Staff are checking patients in, helping people at the desk, answering calls, speaking with insurance companies, and working through follow-ups. The next call arrives before the current task is finished, and some of those calls go to voicemail.
The caller might be a new patient asking whether the practice accepts their insurance or has an appointment available. It might be an existing patient trying to reschedule, request a refill, pay a bill, or get help with something that feels urgent. A missed call can delay a payment, leave an appointment unfilled, or send a patient to another practice.
AI voice agents are designed to take on this work. But in 2026, the options can be difficult to tell apart. Most vendors say they answer calls and book appointments. The real differences lie in what happens after the call is answered. Some focus primarily on voice. Others extend the conversation across text, web chat, outbound follow-up, billing, and more complex scheduling workflows.
This guide compares seven healthcare AI voice agents, what each one can handle, and the types of practices and workflows each is best suited for. We use information from each vendor's own website and published case studies so healthcare buyers can compare them using the same criteria.
Before you compare the rest, you can hear one of these agents yourself. Hear it handle a real call, or book a call to try it on your own lines.
At a glance
The best AI voice agent for healthcare does more than answer calls. It books appointments, supports outbound follow-up, helps patients with billing questions, and continues conversations across voice, text, and web chat. The goal isn't just to answer the phone. It's to finish more of the work without sending it back to the front desk.
Hello Patient builds healthcare-only AI agents for high-volume outpatient practices and groups. Its agents handle inbound and outbound conversations across voice, text, and web chat, from scheduling and patient outreach through billing.
Among the seven vendors and published materials reviewed here, Hello Patient is the only one with a named customer result from a live medical billing phone line. At Piedmont Urgent Care, managed by WellStreet, the billing agent went live in 40 days, answers more than 20,000 billing calls each month, and resolves 48% without staff involvement.
The other vendors each bring different strengths. Assort Health focuses on specialty patient access. Confido Health emphasizes high-volume voice automation. EliseAI supports healthcare alongside other industries across multiple communication channels. Notable Health, Hyro, and Artera are geared more toward enterprise health systems and large-scale patient engagement.
Hello Patient publishes this guide and is included in the comparison. We use each vendor's publicly available product information and published case studies, and distinguish between capabilities that are listed, demonstrated, and supported by named customer results.
How we picked these AI voice agents
We evaluated every company using the same criteria and kept three levels of evidence separate. A vendor may list a capability on its website, demonstrate it in a demo, or support it with a named customer result. Those are not the same thing, and we've identified which level of evidence is available for each company.
Finishing the work, not just answering the call. Answering the phone is only the first step. What matters is whether the agent can schedule the visit, gather the right information, help with billing, and hand off the conversation cleanly when a staff member is needed. A tool that answers the call and immediately routes it to someone else has only moved the work to another queue.
Communication channels. We looked at whether patients can complete the same task across voice, text, and web chat, or whether the conversation stops when they switch channels and staff have to take over.
Inbound and outbound. Answering incoming calls is only half the job. Practices also need to reach patients for recalls, follow-ups, reminders, and rescheduling. A tool that only answers the phone leaves all of that outbound work to staff.
EHR integration. An appointment is only valuable if it is written directly into the scheduling system your staff uses, without requiring someone to enter it manually.
Billing capabilities. Many vendors list billing or payment features. Fewer publish evidence from a named customer using an AI agent on a live medical billing phone line.
Healthcare focus. Healthcare-only vendors are typically built around patient access, billing, and clinical workflows. Cross-industry vendors may bring broader automation experience. Buyers should evaluate how much of the product is designed specifically for healthcare.
Compliance. A vendor should sign a Business Associate Agreement (BAA) before handling protected health information (PHI) on behalf of a practice. A SOC 2 Type II report also provides evidence that an independent auditor has evaluated the vendor's security controls over time. We report each vendor's claims as published. If something is not listed here, that does not mean the vendor does not have it. We also published a separate guide to HIPAA-compliant AI voice agents that explains what to ask every vendor before making a decision.
Proof you can verify. A named customer case study provides more confidence than an unsupported percentage or marketing claim. Whenever possible, we prioritized published results that healthcare buyers can review for themselves.
Seven healthcare AI voice agents to compare
These seven vendors serve organizations ranging from single-location practices to health systems with hundreds of locations. Some focus on urgent care and specialty groups, while others are built primarily for enterprise health systems.
Each profile uses the same evaluation criteria described above and highlights where the evidence comes from, whether it's a listed capability, a demonstrated feature, or a published customer result.
Hello Patient
Built around: Finishing more of the patient conversation across inbound and outbound voice, text, and web chat, including scheduling, follow-up, and billing.
Channels: Voice, text, web chat
EHR integration: Reads live schedules and writes appointments directly into the EHR.
Billing proof: Named customer result from a live medical billing phone line. At Piedmont Urgent Care, managed by WellStreet, the billing agent answers more than 20,000 billing calls each month and resolves 48% without staff involvement.
Hello Patient builds healthcare-only AI agents for patient conversations. The agents handle inbound and outbound conversations across voice, text, and web chat. On inbound calls, they answer insurance questions, schedule or reschedule appointments, and write appointments directly into the practice's EHR.
The outbound capabilities extend beyond appointment reminders. Agents call and text patients for recalls, follow-up, rebooking, and referral outreach, continue the conversation when patients reply, answer questions that are preventing them from scheduling, and book appointments while the conversation is still active. Practices using Hello Patient for recall and follow-up have reported booking around 20% more appointments without adding staff.
Published customer results
Pulse MD: The multi-location urgent care provider reduced missed calls from 26% to zero during its first month. The agent resolved around 30% of calls without staff involvement and returned 208 staff hours to the front desk.
Piedmont Urgent Care: Managed by WellStreet, Piedmont implemented a Hello Patient billing agent in 40 days. The agent now answers more than 20,000 billing calls each month, resolves 48% without staff involvement, and sends secure payment links during the conversation to help patients complete payment before the call ends.
Ortho1 Medical Group: The San Diego orthopedic group used outbound text conversations to reach referred patients who had not yet scheduled. The agent contacted 718 patients, 426 replied, and by the second month, 57% of those who responded had booked an appointment. The practice booked 190 referral visits in its first two months without adding staff.
Compliance: Hello Patient states that it is HIPAA-compliant, SOC 2 Type II certified, and signs a Business Associate Agreement (BAA) with every customer.
Learn more: Hear the agent handle a real patient conversation or request a demo to see how it would work for your practice.
Assort Health
Built around: Specialty patient access, with published evidence concentrated in specialty care.
Channels: Voice, text, email, web chat
EHR integration: States that appointments and updates are written back to the EHR.
Billing proof: Lists inbound billing support, payment resolution, and automatic EHR reconciliation. We did not find a named customer result from a live medical billing phone line in the published materials reviewed.
Assort Health is a healthcare-only patient access platform focused on specialty care. It supports inbound and outbound voice, text, email, and web chat. Its published capabilities include scheduling, referrals, payments, and EHR write-back.
Its strongest published customer results are in specialty practices, where patient access workflows are often more complex. At South Shore Orthopedics, a backlog of 600 to 1,000 voicemails was reduced to zero, and approximately 45% of calls were resolved without a staff handoff. At SENTA, the company reports a 97% reduction in hold time.
Published customer results:
- South Shore Orthopedics: Reduced a backlog of 600 to 1,000 voicemails to zero and resolved approximately 45% of calls without a staff handoff.
- SENTA: Reduced patient hold times by 97%.
Compliance: Assort states that it is HIPAA-compliant and SOC 2 Type II certified.
{dashed-rule}
EliseAI
Built around: Broad conversational channels across healthcare and housing.
Channels: Voice, SMS, email, web chat
EHR integration: States that appointments can be booked directly into the EHR with real-time synchronization.
Billing proof: Lists billing and payment capabilities. We did not find a named customer result from a live medical billing phone line in the published materials reviewed.
EliseAI supports voice, SMS, email, and web chat for patient communication. Its healthcare platform includes scheduling, appointment reminders, billing, and payment workflows.
The company entered healthcare after building conversational AI for the housing industry, where it continues to operate alongside its healthcare business. Buyers should evaluate how well the platform's healthcare capabilities align with their organization's workflows and requirements.
Published customer results:
- Texas Dermatology: Schedules more than 250 new patients per month through EliseAI.
- Dermatology practice: Reduced staff-handled calls by 52%.
Compliance: EliseAI states that it is HIPAA-compliant and SOC 2 Type II compliant.
{dashed-rule}
Confido Health
Built around: High-volume inbound and outbound voice calls, with text support.
Channels: Voice, text (we did not find a standalone website chat widget in the published materials reviewed)
EHR integration: States that its platform reads from and writes back to EHR and practice management systems in real time.
Billing proof: Lists insurance verification, balance inquiries, payment reminders, copay clarification, and payment-plan outreach. We did not find evidence of secure payment links, payments completed during a live billing call, or a named customer result from a live medical billing phone line in the published materials reviewed.
Confido Health is a healthcare-only, voice-first AI platform for 24/7 inbound and outbound patient calls. It also supports text messaging and positions its platform for multi-location practices and larger healthcare groups. The company states that it integrates with more than 40 EHR and phone systems.
Its strongest published customer results focus on high-volume call handling. Formé Medical uses a bilingual Confido agent. At Dallas Renal Group, Confido reports that the agent handles 40% of approximately 20,000 weekly calls, while the number of calls requiring staff attention fell from about 130 to 70 per day.
Published customer results:
- Formé Medical: Uses a bilingual AI agent for patient calls.
- Dallas Renal Group: The agent handles 40% of approximately 20,000 weekly calls, reducing the number of calls requiring staff attention from about 130 to 70 per day.
Compliance: Confido states that it is HIPAA-compliant and SOC compliant. Its public materials were inconsistent about whether its SOC 2 Type II examination has been completed, so buyers should request the current report during their evaluation.
{dashed-rule}
Notable Health
Built around: Enterprise automation across patient access, revenue cycle, and care operations.
Channels: Voice, SMS, web self-service, patient portals (including MyChart)
EHR integration: States that appointments, scheduling updates, and other workflow actions are written directly back to the EHR through bidirectional integrations.
Billing proof: Published customer evidence focuses on copay collection at registration. We did not find a named customer result from a live medical billing phone line in the published materials reviewed.
Notable Health is a healthcare-only enterprise automation platform that includes voice as part of a broader AI platform. Unlike vendors focused primarily on conversational AI, Notable is designed to automate workflows across patient access, revenue cycle, and care operations.
Its patient-facing channels include voice, SMS, web self-service, and patient portals such as MyChart. The company's Sidekick product is a staff-facing AI copilot designed to assist care teams and administrative staff rather than communicate directly with patients.
Published customer results:
- MUSC Health: Notable reports collecting approximately 15% of the health system's total copays, about $1.7 million, without staff involvement. The company also highlights automated outbound mammogram outreach.
- North Kansas City Hospital: Reports that 93% of online appointments were booked without staff involvement.
Compliance: Notable states that it is HIPAA-compliant and SOC 2 Type II certified.
{dashed-rule}
Hyro
Built around: Reducing call center volume and improving patient access for large health systems and community health centers.
Channels: Voice, web chat, SMS (including Call-to-Text SMS deflection), mobile apps, and patient portals.
EHR integration: States that its AI agents integrate with major EHRs, including Epic, and automatically update patient records and scheduling workflows through bidirectional integrations.
Billing proof: Lists billing inquiries, billing reminders, and bill-pay workflows. We did not find evidence that payments are completed within a live AI conversation or a named customer result from a live medical billing phone line in the published materials reviewed.
Hyro is a healthcare-focused conversational AI platform designed to reduce contact center volume and improve patient access for large health systems, community health centers, children's hospitals, and health plans. The company positions its AI agents across inbound voice, web chat, SMS, mobile apps, and patient portals, and names health systems including Intermountain Health, Baptist Health, and Hackensack Meridian Health as customers.
Its Call-to-Text feature helps reduce call volume by sending patients an SMS with links and instructions to complete common tasks through self-service. For outbound engagement, Hyro's Proactive Px platform uses voice and SMS for appointment reminders, referral follow-up, prescription refills, and other patient outreach. At the time of review, Hyro's Proactive Px page continued to label Billing Support and Care Gap Closure as "Coming Soon," even though demonstrations for both are available on the site, so buyers should confirm which capabilities are generally available.
Published customer results:
- Weill Cornell Medicine: Reports a 47% increase in appointments booked online after implementing Hyro.
- Health systems overall: Hyro reports that customers automate more than 65% of incoming calls on average, though this is a company benchmark rather than a named customer case study.
Compliance: Hyro states that its platform is HIPAA-compliant and SOC 2 compliant. Buyers evaluating enterprise deployments should request current compliance documentation, including the latest SOC 2 report.
Built around: Enterprise patient communications with roots in messaging.
Channels: Voice, SMS and rich messaging, email, web experiences, and patient portals.
EHR integration: States that the platform integrates bidirectionally with major EHRs and automates scheduling, intake, and other patient communication workflows across the care journey.
Billing proof: Lists billing reminders, payment requests, and patient payment workflows. We did not find evidence that an AI agent completes a payment during a live patient conversation or a named customer result from a live medical billing phone line in the published materials reviewed.
Artera is a healthcare-only patient communications platform with roots in patient messaging. Founded as WELL Health in 2015, the company rebranded to Artera in 2022 as it expanded beyond messaging into a broader enterprise communications platform.
The platform supports inbound and outbound voice, SMS, rich messaging, email, web experiences, and patient portal communications. Its published capabilities include scheduling, intake, billing, payments, care gap outreach, and follow-up throughout the patient journey.
Published customer results:
- Atlantic Health System: Artera reports reducing staff time by 38% during a colonoscopy outreach campaign, while 39% of patients confirmed their appointments through the automated campaign.
- Enterprise health systems: Artera highlights large-scale patient outreach and communication automation across hundreds of health systems, though the strongest published evidence reviewed focuses on outreach and appointment confirmation rather than live billing conversations.
Compliance: Artera states that it is HIPAA-compliant and SOC 2 Type II compliant. Its Trust Center also documents its SOC 2 Type II audit and additional security certifications.
{dashed-rule}
Billing is not one workflow
Several vendors list billing or payment capabilities, but "billing" can refer to very different workflows.
Collecting a copay at registration happens before or during a visit, when the patient is present and the amount is known. Notable, for example, has published results for that type of workflow.
A medical billing phone line is different. Patients call after a visit with questions about a charge, an insurance payment, or an outstanding balance. The AI agent has to explain the bill, answer questions, and help the patient complete payment during the same conversation without handing the work back to staff. In Hello Patient's published Piedmont Urgent Care case study, 40% of patients who received a secure payment link paid during that interaction.
Among the seven vendors and the published materials reviewed for this guide, Hello Patient is the only company with a named customer case study showing an AI agent operating a live medical billing phone line at scale: live in 40 days, handling more than 20,000 billing calls each month, with 48% of billing calls resolved without staff involvement.
That does not mean the other vendors cannot support billing. Their published evidence demonstrates different parts of the billing process. Buyers evaluating AI for patient billing should look beyond whether a vendor lists "billing" as a capability and ask for published proof that matches the workflow they want to automate.
Ready to evaluate your billing line?
We'll review your current billing call volume, identify the conversations an AI agent could resolve, and show how the workflow would fit your organization.
Book a demo.
{dashed-rule}
Frequently asked questions
What's the best AI voice agent for healthcare?
There is no single best AI voice agent for every healthcare organization. Hello Patient is a strong fit for outpatient practices and groups that want one vendor across inbound and outbound voice, text, web chat, scheduling, follow-up, and billing. Assort Health is centered on specialty patient access. Confido Health is voice-first. EliseAI serves healthcare and housing across a broad set of channels. Notable Health, Hyro, and Artera are built more directly for large health systems. The right choice depends on the work you need finished and the customer proof behind it.
Which AI voice agent handles medical billing calls?
Hello Patient has the clearest published proof in this comparison for an AI agent running a live medical billing phone line. Piedmont Urgent Care, the largest urgent care network in Georgia, run by WellStreet, went live in 40 days. The agent answers more than 20,000 billing calls a month and resolves 48% without staff involvement. Other vendors in this guide list billing, payments, copay collection, or revenue-cycle workflows. Notable has published proof for collecting copays at registration. Among these seven, none shows an equivalent published result for an AI agent running a live billing phone line.
Which AI voice agents do outbound calls and texts, not just answer the phone?
Hello Patient, Assort Health, EliseAI, Confido Health, Hyro, and Artera all show outbound calling and outbound messaging capabilities in the materials summarized here. Hello Patient uses outbound calls and texts for recall, referral follow-up, and rebooking, and can book the patient while the conversation is open. Assort supports outbound voice and text as part of specialty patient access. Confido supports inbound and outbound calls and also handles texts. Hyro's Proactive Px uses voice and SMS for reminders, referrals, and refills. Artera supports inbound and outbound communication across voice and messaging. Notable shows outbound mammogram outreach, but the supplied information does not establish whether that specific campaign used both calls and texts. EliseAI describes VoiceAI as handling both inbound and outbound patient calls across its healthcare platform.
Which AI voice agent books into my EHR automatically?
Hello Patient and EliseAI state that their agents book appointments directly into the EHR. Assort states that it supports EHR write-back, and Confido states that its integrations read from and write to EHR and PMS systems in real time. Notable, Hyro, and Artera describe bidirectional integration or automatic patient-record updates, but the materials reviewed here do not establish the same voice-to-EHR booking workflow for every product. Ask each vendor to find a real opening, follow your visit-type and provider rules, complete the booking or reschedule, and show where the result lands in your exact system.
Which AI voice agents are HIPAA compliant and sign a BAA?
A vendor that creates, receives, maintains, or transmits PHI on behalf of a healthcare organization generally needs a BAA before go-live. Ask every vendor to provide its BAA and current security documentation in writing. Hello Patient is HIPAA-compliant, has completed a SOC 2 Type 2 examination, and signs a BAA with every client. Assort states that it is HIPAA compliant and SOC 2 Type II certified. EliseAI states that it is HIPAA compliant and SOC 2 Type II compliant. Confido states that it is HIPAA and SOC compliant, but its public pages conflict on whether Type II is complete. Notable states that it is HIPAA compliant and SOC 2 Type II certified. Hyro states that it is HIPAA and SOC 2 compliant. Artera lists HIPAA compliance and SOC 2 Type 2 compliance in its Trust Center.
Which AI voice agent is built for a large health system?
Notable Health, Hyro, and Artera are the clearest large-health-system fits in this comparison, but they approach the problem differently. Notable spans patient access, revenue cycle, and care operations. Hyro is centered more directly on reducing call-center demand. Artera is a broad enterprise patient communications platform with roots in messaging. The right fit depends on whether the health system is buying broader workflow automation, call-center relief, or an enterprise communications layer.
Which AI voice agent is built for a specialty practice?
Assort Health is positioned most directly around specialty patient access and has published examples from specialty groups. EliseAI also serves specialty practices and offers a broad set of communication channels. Hello Patient is the broader fit when a specialty group wants the same vendor to handle inbound and outbound conversations across voice, text, and web chat, including scheduling, referrals, follow-up, and billing.
Which AI voice agents also support text and web chat?
Hello Patient, Assort Health, and EliseAI describe channel sets that include voice, text, and web chat. Notable supports voice, SMS, web self-service, and patient portals. Hyro supports inbound voice and web chat and can move conversations into SMS. Artera supports voice, messaging, email, and web experiences. Confido is centered on voice and also handles texts, but the materials reviewed did not show a standalone website chat widget. The useful question is not how many channels appear on the product page. It is whether the agent can finish the same workflow across them or sends the patient back to staff before the work is complete.
What should I ask an AI voice agent vendor to show?
Bring the hardest workflow your staff handles, not the easiest appointment on the calendar. Ask the vendor to show a complicated scheduling rule, an outbound follow-up, a billing question, or a conversation that has to move from phone to text. Then ask the agent to complete the task, put the result in the correct system, and escalate cleanly when the request needs a person. A simple booking proves that the agent can complete a simple booking. It does not prove billing, specialty scheduling, outbound conversion, or EHR write-back.
Bring us one of the calls, scheduling rules, or billing questions your team handles today. We’ll show you what the agent can finish, where the work lands, and when your staff still steps in. Book a call.

.jpeg)